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Alzheimer’s Risk Gene Undermines Insulation Of Brain’s “Wiring”

In people carrying APOE4, a key brain cell mismanages cholesterol needed to insulate neurons properly — another sign APOE4 contributes to disease by disrupting brain lipids.

Study Reveals How Environment and State Are Integrated to Control Behavior

A simple animal model shows how stimuli and states such as smells, stressors, and satiety converge in an olfactory neuron to guide food-seeking behavior.

How the Brain Focuses on What’s in Mind

When holding information in mind, neural activity is more focused when and where there are bursts of gamma frequency rhythms.

When a Task Adds More Steps, This Brain Circuit Helps You Notice

By tracking feedback during tasks, the anterior cingulate cortex notices when a new step has become necessary and signals the motor cortex to adjust.

New Findings Reveal How Neurons Build and Maintain Their Capacity to Communicate

Nerve cells regulate and routinely refresh the collection of calcium channels that enable them to send messages across circuit connections.