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Biologists Train AI To Generate Medicines And Vaccines

Machine learning, used to design proteins with a variety of functions, is doing things scientists didn't realize it was capable of.

Booster Shots Offset Some Omicron Immune Evasion Tactics

While Omicron variants ratchet up immune evasion, study suggests current boosters intensify protections against serious infection

UW Medicine COVID-19 Vaccine Wins South Korea Approval

SKbioscience’s SKYCovione vaccine becomes the first therapeutic OK'd for people to emerge from the Institute for Protein Design.

Some Elusive Genome Areas Hold Distinctly Human Data

UW Medicine’s contribution to finishing the sequence covered highly repetitive regions, include those related to human evolution.

Gene Deletion Behind Anomaly In Blood Cancer Cells

Discovery that Lamin B1 mutation causes odd-shaped nuclei may lead to improved leukemia care.

Design Of Protein Binders From Target Structure Alone

A new method for generating potent, specific binding proteins yields candidate medicines for cancer, diabetes, inflammation and more.

AI-Designed Protein Awakens Silenced Genes, One By One

Technique allows researchers to toggle on individual genes that regulate cell growth, development and function.

‘Roadmap’ Tracks Trajectories Of Embryo Development

Map details the changes in gene activity that occur as the embryo develops and differentiates into different cell types.

Improved Cell Response Seen With ‘Hybrid’ Immunity

A distinct immune response is observed in people who had COVID-19 and then got vaccinated.

Home-Based Flu Tests Comparable To Clinical Testing

Study findings underscore imperative of expanding test access and lowering costs.

Henipavirus Glycoprotein Structure Guides Therapy, Vaccine

Cryoelectron microscopy studies of Nipah and Hendra viruses may lead to ideas for vaccine design and antibody treatments.

Study Details Changes In Omicron’s Spike Protein

Findings explain how mutations allow the omicron variant to evade antibodies against previous variants yet remain so infectious.

Breakthrough Infections Spur Strong Antibody Responses

People vaccinated three times or vaccinated after an earlier COVID-19 infection had comparable neutralizing antibody activity to those with a breakthrough case.

Antibody That Inhibits Broad Range Of Sarbecoviruses Found

The antibody closely mimics the binding site that the SARS-CoV-2 virus uses to infect cells, and seemingly thwarts invasion via mutation.

Genomics Aids Study Of Seattle 2017-22 Shigella Outbreak

A genomic study of a sustained, multidrug-resistant Shigellosis outbreak in Seattle enabled scientists to retrace its origin and spread.