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Cell Division in Embryos: Not a Textbook Case of Symmetry

As cell biologists, Université de Montréal professor Greg FitzHarris and his PhD student Lia Paim are very interested in fertility and what happens inside the eggs and embryos of the mice they study in their lab.


University of Montreal
Jul 20, 2023

Two researchers from the CHUM Research Centre find that cell division in mouse embryos is not at all symmetrical, quite unlike what science textbooks say. 

As cell biologists, Université de Montréal professor Greg FitzHarris and his PhD student Lia Paim are very interested in fertility and what happens inside the eggs and embryos of the mice they study in their lab. And sometimes, they spot something unusual … by accident.

Their latest findings, published in PNAS, could change how one particular aspect of cell division is understood and pave the way for further research on how this might play a role in the viability of the embryo – even a human one

To learn more, we asked Fitzharris what he and his co-author’s work is all about.

Publication: Lia Mara Gomes Paim, et al., Cell size and polarization determine cytokinesis furrow ingression dynamics in mouse embryos, Cell Biology (2022). DOI: 10.1073/pnas.2119381119.

Original Story Source:  University of Montreal


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