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Texas Tech University | Department of Biological Sciences

Cotton Crop Resilience Soars with AVP1 and RCA Co-Overexpression

Cotton Crop Resilience Soars with AVP1 and RCA Co-Overexpression


Current Science Daily
Sep 20, 2023

A recent scientific study conducted by researchers at Texas Tech University has discovered a groundbreaking solution to combat crop failure caused by abiotic stresses. By co-overexpressing two specific genes, AVP1 and RCA, in cotton plants, scientists have significantly enhanced the plant's ability to tolerate drought, heat, and salt stress. This genetic modification has resulted in a substantial increase in cotton fiber yield, offering hope for improving crop production in arid and semiarid regions.

Abiotic stresses, such as drought, heat, and salinity, have long posed challenges to crop production. While genetic engineering has made progress in addressing other agricultural issues, mitigating the detrimental impacts of these environmental stressors on crops has proven difficult. Previous research has shown that co-overexpression of the AVP1 gene in Arabidopsis, which encodes a vascular H+-pyrophosphatase, can increase drought and salt tolerance. Building on this knowledge, scientists hypothesized that augmenting specific genes, including AVP1 and RCA, could enhance plant resilience to individual stressors.

The study, authored by Jennifer Smith, Inosha Wijewardene, Yifan Cai, Nardana Esmaeili, and Hong Zhang at Texas Tech University, involved co-overexpressing AVP1 and RCA genes in cotton plants. The results were impressive, with cotton plants exhibiting this genetic modification yielding 50% and 96% more seed fiber than their wild counterparts when subjected to drought and salt stress and drought and heat stress, respectively.

In addition to increased yield, these genetically enhanced cotton plants also showed a 6.5-fold increase in net photosynthetic rates when faced with heat stress. Furthermore, they displayed significantly higher rates of Vcmax, a measure of photosynthetic capacity, under various stressful conditions. The practicality of this genetic modification was confirmed through field studies conducted in two different environments, where cotton plants with RCA/AVP1 co-overexpression achieved substantial boosts in seed fiber yield.

This groundbreaking research offers hope for improving crop resilience in arid and semiarid regions. By enhancing cotton plants' ability to withstand abiotic stresses, such as drought, heat, and salt stress, this genetic modification has the potential to increase crop yields and contribute to food security in challenging environments. Further research and development in this area could lead to similar advancements in other crops, paving the way for more sustainable agriculture practices.

Link to the study:


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