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Putting The STING Into Cancer Immunotherapy

A cancer vaccine combining checkpoint blockade therapy and a STING-activating drug eliminates tumors and prevents recurrence in mice.

Engineers Design Sutures That Can Deliver Drugs Or Sense Inflammation

The bioderived “smart sutures” could help patients heal after bowel resection or other types of surgery.

Governing For Our Descendants

In a recent essay, Professor Lily L. Tsai shares ideas on how to include future generations, who will face the climate crisis we’ve created, in our definition of our collective society.

Researchers Create A Tool For Accurately Simulating Complex Systems

The system they developed eliminates a source of bias in simulations, leading to improved algorithms that can boost the performance of applications.

Study: AI Models Fail To Reproduce Human Judgements About Rule Violations

Models trained using common data-collection techniques judge rule violations more harshly than humans would, researchers report.

A Better Way To Study Ocean Currents

A new machine-learning model makes more accurate predictions about ocean currents, which could help with tracking plastic pollution and oil spills, and aid in search and rescue.

Standard Sepsis-ID Systems Miss Cases In Trauma Patients

A new automated system identified far more sepsis infections than 2 commonly used methods, researchers report.

Stigma, Lack Of Support Limit HIV Testing In Côte d’Ivoire

Collaboration finds that improved training and support of community health workers are needed to improve HIV testing.

How To Untangle A Worm Ball: Mathematicians Solve A Knotty Mystery

California blackworms tangle themselves up by the thousands, then separate in a split second. Their trick may inspire the design of self-detangling materials and fibers.

Overlooked Tau-RNA Interaction Plays Key Role In Dementia

RNA contact with tau protein spurs neurofibrillary tangles in the brain — a defining hallmark of Alzheimer’s and other diseases.

Genomics Aids Study Of Seattle 2017-22 Shigella Outbreak

Analysis of the outbreak shed light on its origins and transmission patterns, and assessed treatment and infection control.

Removing Race Adjustment From Common Prenatal Test

Dr. Shani Delaney, an associate professor of OB-GYN and maternal fetal medicine at the University of Washington School of Medicine, is a senior author of a study that found that results of a prenatal test used for over five decades should not be adjusted based on a patient's race.

How Regulatory T Cells Halt Aberrant, Self-Reactive T Cells

Study reveals new therapeutic target to subdue autoimmune inflammation caused by loss of regulatory T cell function.

Genetic Diagnosis Helps Guide Care Of Childhood Hearing Loss

Treatment of childhood-onset hearing loss can be more precisely tailored with information on specific genetic cause.

Vaccines Protected Pregnant Women During Omicron Surge

Worldwide study shows COVID vaccines and boosters reduced the risk of severe COVID-related disease in pregnant women by about 76%.

Roundworm Lifespan Extended In Mitochondria Study

Harnessing light energy to rejuvenate mitochondrial membrane potential slowed aging in C. elegans.

Study Illuminates Sugar’s Role In Common Kidney Disease

In a novel lab environment using mini kidney structures, drugs blocked the swelling of tubes seen with polycystic kidney disease.

Targeting Tau, The Other Protein Behind Alzheimer’s Disease

Most Alzheimer’s drugs in development target beta-amyloid, but targeting another protein, called tau, may be needed.

Some Abortion Experts Don't Disclose University Ties

Articles on smoking and gun control noted specialists' university affiliations about 90% of the time, but only 77% of the time with references to abortion.

Physically Active People Use Medical Services Less

People who regularly engage in physical activity are less likely to go to the doctor, emergency room or hospital, UW Medicine study finds.