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Liver Fibrosis Linked to Reduced Cognitive Ability and Brain Volume

A new Yale-led study finds that liver fibrosis is associated with reduced cognitive function and brain volume, a link mediated, in part, by inflammation.

Diminished Brain Response To Nutrients Observed In People With Obesity

A new study reveals a diminished response to nutrients among people with obesity — and that this brain response is not recovered after weight loss.

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Just A Slice: Surgeon-Scientists Reap Small Share of U.S. Research Grants

Around 30% of the global burden of disease is treatable with surgery. But surgeon-scientists receive very little research funding, a new study finds.

Socioeconomic Diversity of U.S. Medical School Students Has Decreased

The socioeconomic diversity of U.S. medical school students has decreased over time, a new study finds. The result could be detrimental to patients.

Study Identifies Compounds That May Improve Treatment of Opioid Addiction

Searching for compounds with the therapeutic effects of ibogaine but not its toxicity, researchers found two that eased depression and opioid withdrawal.

Study Reveals Potential Target for Precision Colorectal Cancer Treatment

Around 40% of colorectal cancer patients have a particular gene mutation. A new study shows it’s linked to reduced cell death and worse survival rates in men.

Early in mpox Outbreak, Access to Vaccines Was Unequal Across Racial Groups

Yale researchers found mpox vaccine distribution was in proportion to cases at the peak of the outbreak, but Black and Hispanic populations had less access.

Newly Identified Tsetse Fly Pheromone May Help Curb Disease Spread

Discovery of the pheromone revealed new information about how the flies communicate — which people could use to limit their populations.

Researchers Decode Targets for Hundreds of Signaling Enzymes

Kinases are essential for cell signaling. A new study matches hundreds of kinases to their targets, enabling a deeper understanding of biological processes.

Machine Learning Model Predicts Physician Turnover

Yale researchers’ machine learning model identifies contributors to physician departure, which could help improve job satisfaction and stem costly turnover.

COVID-19 Treatment Gaps Highlight Persistent Health Care Challenges

A new analysis of how far Americans have to travel to receive COVID-19 oral treatments like Paxlovid reveals stubborn discrepancies in health care access.

Opioid-Involved Car Crashes Plummeted Following Efforts To Curb Use

The number of non-fatal car accidents that involve prescription opioids has dropped significantly in recent years, suggesting efforts to curb use are working.

Inflammation may explain antidepressants’ link to preterm birth

Antidepressants can increase the risk of preterm birth, but it’s unclear why. A new Yale study shows inflammation may play a key role.

How The Brain Gives Rise To Cravings: Neuromarker Sheds New Light

Yale researchers have uncovered a pattern of brain activity that predicts drug and food craving, a potentially valuable biomarker for addiction.

Inequities in Medical School Research Could Hinder Workforce Diversity

Diversity in the biomedical workforce leads to more research innovation, higher quality work, and more participation in clinical trials by people in underrepresented racial and ethnic groups.

Helping Students Build Strong Foundations in Ethical Global Health Work

When she was a student at Yale School of Medicine more than a decade ago, Dr. Mei Elansary ’12 conducted a project on the Indonesian island of Borneo.

Studying Schizophrenia in Plants? Yale Researchers Are Giving It a Shot

What if scientists could study human psychiatric illness in plants?

Receptor structure reveals new targets for cancer treatment

A molecule known as anaplastic lymphoma kinase (ALK) is a driver of several cancers, including pediatric neuroblastoma, B-cell lymphomas, and myofibroblast tumors.