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International group of scientists identifies cancer-resistance genes across species

Cancer is a leading cause of human disease and death worldwide, but it's also common in animals. Can we learn something about the genetic mutations associated with cancer in animals that sheds light on the origins of human cancer and how to prevent and treat it?

German study finds gut microbiome disruption associated with COVID-19 complications, mortality

The role the gut microbiome plays in COVID-19 is a subject of ongoing discussion, and it's not clear whether the microbiome influences the course of the disease or vice versa.

Weizmann Institute scientists pursue evolution of sphingolipids, implications for Darwinian theory

Sphingolipids are a type of fatty material (lipids) in cell membranes that are critical for membrane structure and cell signaling. When they malfunction, sphingolipids can cause human illnesses, such as Gaucher disease, a rare inherited metabolic disorder.

International team expands the genetic alphabet to create new DNA-like structures

The hereditary material of humans and other organisms is stored as a code in DNA, deoxyribonucleic acid, in each cell's nucleus. The traditional geometric structure of DNA is the double helix, discovered in 1953. Now synthetic biologists are examining how the familiar DNA geometry can be engineered into new forms with new properties and potential uses.

Hungarian team applies game theory to determine how a government can fight novel pathogen

The COVID-19 pandemic has made the world aware of the deadly consequences of a new pathogen for which there was little preparation and no initial vaccine.

Canadian professors' new book explores regeneration of microbial communities

A biologist and a philosopher have collaborated on a new book that looks at how microbial communities regenerate--and why.

London, U.S. scientists suggest cognition far more than neuron processing in the brain

What if cognition--thinking--is not simply a function of neurons interacting in the brain, but a process involving the entire human organism?

Weizmann Institute team proposes model to explain thyroid disease dynamics

About 5% of the world population suffers from thyroid disease with often severe symptoms, yet treatment is not a simple adjustment of thyroid hormone levels.

Arizona State-led scientists recommend methods to improve statistical inference in population genomics

Population genomics compares the genetic variations in DNA within and between specific biological populations, looking at the influence over time of processes like natural selection, genetic drift and other factors.

Researchers: Flawed 1956 National Academy of Sciences report on radiation risk should be retracted

Many fear radiation without much understanding of what ionizing radiation is, how it works and what the actual risk is. This lack of knowledge and public perception combine to make people fearful of all things nuclear, which has had serious consequences.

Scientists urge financial sanctions for Meta, other tech companies that allow illegal wildlife sales

Illegal wildlife trade was estimated at $20 billion in 2021 and threatens thousands of species worldwide, scientists say. They note social media is the main marketplace for illegal sales of exotic animals and animal parts to provide consumers with pets, medicinal uses and decorations.

Israeli scientists learn important lessons for drug design from acetylcholinesterase

Enzyme inhibitors are used by pesticides and nerve agents to target acetylcholinesterase, an enzyme that starts the breakdown of an organism's neurotransmission. It is also used in the laboratory to preserve a protein for study by shutting down the organism's nerve impulse transmission.

Darwin critics call for a new look at Darwinian evolution

The still-evolving view of evolution is the current "modern synthesis," which encompasses Charles Darwin's theory, Gregor Mendel's concept of heredity, and modern genome research.

Tufts scientists use advance bioelectric signals to repair alcohol-induced defects in embryos

Exposure to nicotine or alcohol and disruptions of a protein necessary for cell communication can cause the malformation of organs and the nervous system of an embryo. It's one reason why pregnant women are urged not to smoke or drink.

Swiss biologists try to bypass null hypothesis to develop more realistic method

Replacing an entrenched method in scientific research is difficult, even when the method is problematic. Such is the case with shifting from research studies based on the null hypothesis to a more realistic method of estimation.

University of Bristol team shows squamates expanded up to 74 million years earlier than thought

Dating the expansion of a group of species when the fossil record is sparse is not a simple task, and can change as methods of analysis become more sophisticated.

Understudied proteins: The Wellcome Trust launches an initiative to broaden protein research

Scientists have focused on studying only a very small set of the proteome due to a variety of factors. This inequality has resulted in thousands of proteins being poorly understood.

International research team uncovers possible therapy for Parkinson's disease

Parkinson's disease is a devastating neurodegenerative disorder that affects nearly 1 million people in the United States, and more than 10 million worldwide.

British-U.S. team evaluates computational methods vs. fragment screening for drug discovery

Designing new drugs that can target specific diseases is a challenging but crucial task for preventing and treating human diseases.

Princeton biologist: 'De novo' genes a proven possibility

How is it possible for a random sequence to produce a functional gene?