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Gulf War Illness Caused by Mitochondrial Dysfunction, Not Inflammation

UC San Diego scientists contest longstanding hypothesis about mysterious illness affecting Gulf War veterans, providing first direct evidence that symptoms are driven by impaired mitochondria

One-Two Punch: Novel Drug Pairing Could Beat Pancreatic Cancer

UC San Diego researchers find a combination of drugs outperformed other treatments in human and mouse models of pancreatic cancer; now urge clinical trial

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Tethering of Shattered Chromosomal Fragments Paves Way for New Cancer Therapies

UC San Diego scientists discover shattered chromosomal fragments are tethered together during cell division before being rearranged; destroying the tether may help prevent cancerous mutations

New Study Flips the Script on Liver Cancer

UC San Diego scientists find protein associated with liver cancer may actually be key to protecting against it

To Ward Off Aging, Stem Cells Must Take Out the Trash

UC San Diego scientists find stem cells’ unique way of discarding misfolded proteins could be the key to maintaining long-term health and preventing disease

Toddlers’ Attention to ‘Motherese’ Speech May Be Used to Diagnose Autism

UC San Diego scientists develop new eye-tracking test that accurately identifies toddlers with a subtype of autism spectrum disorder

Artificial Intelligence Aids Discovery of Super Tight-Binding Antibodies

Tools developed by UC San Diego scientists could accelerate the development of new antibody drugs.

Artificial Intelligence Aids Discovery of Super Tight-Binding Antibodies

Tools developed by UC San Diego scientists could accelerate the development of new antibody drugs.

Stress-Tolerant Cells Drive Tumor Initiation in Pancreatic Cancer

UC San Diego study may inspire new chemotherapeutic drugs targeting early stages of tumor formation and spread

Tissue-Specific Immunity May Be the Future, If We Can First Learn Its Rules

UC San Diego study reveals critical insights into the complex biology of tissue-specific T cells, paving the way for a new branch of precision therapeutics.

Tissue-Specific Immunity May Be the Future, if We Can First Learn its Rules

UC San Diego study reveals critical insights into the complex biology of tissue-specific T cells, paving the way for a new branch of precision therapeutics.

Experts from 14 Nations Discuss Global Gene Drive Project Registry

Advances in gene editing technologies are allowing for the development of potential new strategies for vector-borne disease control, pest management and conservation by genetically modifying organisms in a laboratory.

New Look at an Ancient Disease: Study Finds Novel Treatment Targets for Gout

UC San Diego scientists identify a new model of the arthritic disease, centered on the joint lubricating protein lubricin

Enzyme Drives Cognitive Decline in Mice, Provides New Target for Alzheimer’s

UC San Diego study identifies PKCα as a potential therapeutic target in Alzheimer’s disease

UC San Diego Sanford Stem Cell Institute Launches Stem Cells Into Space

Teaser UC San Diego Sanford Stem Cell Institute Launches Stem Cells Into Space

COVID-19 Rebound After Taking Paxlovid Likely Due to Insufficient Drug Exposure

Paxlovid rebound patient did not show drug resistance or impaired immunity; UC San Diego study suggests insufficient drug exposure was most likely cause

Pharmacists at Higher Risk of Suicide than General Population, Study Finds

The pandemic put a spotlight on mental health and burnout within health care professions, but emerging research reveals these issues have been affecting health care workers for years, with suicide rates notably high among physicians and nurses.

COVID-19, MIS-C and Kawasaki Disease Share Same Immune Response

The inflammatory disorders share similar underlying molecular patterns, a UC San Diego study reports; findings may improve disease diagnosis and treatment and support new drug targets for MIS-C