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Artificial Neural Networks Learn Better When They Spend Time Not Learning at All

Depending on age, humans need 7 to 13 hours of sleep per 24 hours.

Brain Organoids Reveal in Detail the Harms of Prenatal Alcohol Exposure

No amount of alcohol consumption is safe for a developing fetus; a new study presents in molecular detail how alcohol harms growth and functioning of developing brain organoids

Novel Device Measures Nerve Activity That May Help Treat Sepsis and PTSD

A team of engineers and physicians at University of California San Diego has developed a device to non-invasively measure cervical nerve activity in humans, a new tool that they say could potentially inform and improve treatments for patients with sepsis, a life-threatening response to infection, and mental health conditions, such as post-traumatic stress disorder (PTSD).

Parsing the Genetic Drivers of Head and Neck Cancers

Human papilloma virus causes some cases, but the most lethal form of head and neck cancer is linked to chromosomal alterations; a new study sharpens that association and hints of more effective treatment options

Organoids Reveal How SARS-CoV-2 Damages Brain Cells — and a Potential Treatment

COVID-19 infections can result in long-lasting neurological symptoms; new research suggests an already approved anti-viral may inhibit viral replication and rescue impaired neurons

Appendiceal Cancer Gets Its Own Preclinical Model

UC San Diego researchers develop a 3-D culture for a rare disease that has long defied effective study and development of therapies

Artificial Neural Networks Learn Better When They Spend Time Not Learning at All

Depending on age, humans need 7 to 13 hours of sleep per 24 hours. During this time, a lot happens: Heart rate, breathing and metabolism ebb and flow; hormone levels adjust; the body relaxes. Not so much in the brain.

Popular Pharmaceutical Target in Cells May Prove Even More Useful

G protein-coupled receptors are already leveraged in hundreds of diverse drugs; the discovery that they function in a way not previously known suggests untapped potential

Lactating Mice Pass along Common Antimicrobial to Pups, Initiating Liver Damage

Triclosan is used in everything from cleaners to pesticides to toys; researchers say exposure early in life may lay groundwork for future development of fatty liver disease

Organoids Reveal Similarities Between Myotonic Dystrophy Type 1 and Rett Syndrome

Discoveries of common mutations and dysfunction also point to therapeutic possibilities for both inherited disorders

Gene Therapy Shows Promise in Treating Neuropathy from Spinal Cord Injuries

In mouse studies, pain-blocking neurotransmitters produced long-lasting benefit without detectable side effects

Can seven questions determine how wise you are?

Seven-item Jeste-Thomas Wisdom Index has high validity to measure wisdom and potential to improve overall well-being

UC San Diego researchers produce single-cell chromatin atlas for human genome

In an unprecedented atlas, researchers begin to map how genes are turned on or off in different cells, a step toward better understanding the connections between genetics and disease