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Dissolving Implantable Device Relieves Pain Without Drugs

New device could provide an alternative to opioids and other highly addictive drugs

Unexpected Link Between Most Common Cancer Drivers May Yield More Effective Drugs

Two of the most common genetic changes that cause cells to become cancerous, which were previously thought to be separate and regulated by different cellular signals, are working in concert, according to new research from the University of Wisconsin–Madison.

​​​​​​​Researchers Discover New Leukemia-Killing Compounds

Rice, MD Anderson study highlights potential of mitochondria-targeted chemotherapies

Tissue Model Reveals Key Players in Liver Regeneration

By tracing the steps of liver regrowth, MIT engineers hope to harness the liver’s regenerative abilities to help treat chronic disease.

Scientists Show How Fast-Growing Bacteria Can Resist Antibiotics

Scientists have demonstrated how some fast-growing bacteria can resist treatment with antibiotics, according to a study published today in eLife.

Vitamins, Supplements Are a ‘Waste of Money’ for Most Americans

There’s no ‘magic set of pills to keep you healthy.’ Diet and exercise are key.

COVID-19 Rebound After Taking Paxlovid Likely Due to Insufficient Drug Exposure

Paxlovid rebound patient did not show drug resistance or impaired immunity; UC San Diego study suggests insufficient drug exposure was most likely cause

British-U.S. team evaluates computational methods vs. fragment screening for drug discovery

Designing new drugs that can target specific diseases is a challenging but crucial task for preventing and treating human diseases.

Dried Samples of Saliva and Fingertip Blood Are Useful in Monitoring Responses to Coronavirus Vaccines

Based on an antibody study, dried samples of easily self-collected saliva and of blood drawn from the fingertip could be useful for monitoring people’s immune responses to vaccination.

Native Americans Face Disproportionate Travel Burden for Cancer Treatment

SPOKANE, Wash.—Experiencing higher rates of certain cancers than non-Hispanic whites, many Native Americans have to travel especially large distances to access radiation therapy, according to a study led by Washington State University researchers.

Chicken Vaccination Shows Benefits for Nutrition, Growth in Kenyan Children

Vaccinating household chicken flocks can increase availability and consumption of eggs and meat, leading to better growth of young children in agriculture-dependent families in rural Kenya.

Israeli-Harvard mathematical model evaluates safety of anti-COVID-19 drug

A collaboration between the Weizmann Institute in Israel and Harvard University developed a mathematical model to test the safety of a class of anti-viral drugs that accelerate the mutation rate of the virus, causing “death by mutagenesis.”

A Single Course of Antibiotics Affects the Gut Microbiota of Infants

A study indicates that antibiotics, which kill bacteria, boost the abundance of gut fungal microbiota. The phenomenon can be a contributing factor in the long-term adverse effects of antibiotics, such as inflammatory bowel diseases.

How a Narrow-Spectrum Antibiotic Takes Aim at C. Diff

Most antibiotics are double-edged swords. Besides killing the pathogen they are prescribed for, they also decimate beneficial bacteria and change the composition of the gut microbiome. As a result, patients become more prone to reinfection, and drug-resistant strains are more likely to emerge.

Antibody Therapy Controls HIV for Months in New Clinical Trial

Antiretroviral therapy has made HIV a manageable condition, but it does not eliminate the virus from the body—and most regimens are expensive and require a pill every day, for the rest of the patient’s life.

Disparities in Diabetic Eye Care

Minorities Have Fewer Exams, Higher Rates of Illness

Researchers discover new tools in regular blood samples for developing precision therapies for lymphoma

Tumour DNA circulating in the bloodstream of patients with aggressive lymphoma has a previously unknown and even crucial role in the identification of effective therapies for this serious disease.

New responsible data sharing technique will enable better understanding of disease-causing genetic variants

Using federated analysis on protected health data sets can lead scientists to a more nuanced understanding of heritable disease